Seattle, WA


The annual Cascadia Proteomics Symposium brings together Proteomics Researchers from the Northwest region, Washington, Oregon, and British Columbia, to discuss current Proteomics Research, get to know each other better, share ideas and foster collaboration within this region. The program includes interactive oral and discussion sessions, as well as poster presentations with appetizers, northwest brews, wine and cheese sessions to foster mingling.

The 2020 symposium was scheduled to be a special session within the US-HUPO meeting in March 2020 in Seattle. But then SARS-CoV-2 ruined everything. There is growing momentum to reboot the Cascadia Symposium in 2023 in July. Maybe at ISB again? Let us know what you think.

The 2019 Program

Monday, July 8
Tuesday, July 9
Registration & Continental Breakfast
Chair: Rob Moritz (ISB)
Alexey Nesvizhskii (U Michigan)
Applications of Ultrafast Database Searching in Proteomics and Proteogenomics
Session 1: Systems Biology
Chair: Chris Barnes (Novo Nordisk)
Mark Gillespie (ISB)
A systems approach to quantifying transcriptional regulation in atherosclerosis
Marli Vlok (UBC)
Positional proteomic analysis reveals novel cleavage products that promote enterovirus infection.
Lightning Talk: Juan Chavez (UW)
Systems structural biology of the heart: Impact of acetylation on protein conformations/interactions
Lightning Talk: Clint Vorauer (UW)
Biophysical Properties of Refractile Bodies
Session 2: Degradomics and PTMs
Chair: Alexey Nesvizhskii (U Michigan)
Daniele Canzani (UW)
Degronomics: Integrative Mass Spectrometry for Identifying Cellular E3 Ligase interactions
Nestor Solis (UBC)
TAILS terminomics, shotgun proteomics and transcriptomics analysis of macrophage differentiation
Abhigya Mookherjee (UW)
Hybrid mass spectrometric-based methods for distinguishing isomeric oligosaccharides
Lightning Talk: Anthony Valente (UW)
Towards targeted phosphoproteomics by machine learning
Lightning Talk: Christopher Adams (Bruker)
Identification and Quantitation of Phosphopeptide Positional Isomers using TIMS and PASEF
Lightning Talk: Drake Russell (UW)
An Exploration of the Post Translational Structure of a Novel S-Methyltransferase
Lightning Talk: Alex Zelter (UW)
Elucidating protein-xenobiotic interactions by mass spectrometry
Session 3: Disease Proteomics
Chair: Wei-Jun Qian (PNNL)
Phillipp Lange (UBC)
The first 50 cases in BRAvE: Using genomics and proteomics to advance pediatric precision oncology
Jaipalreddy Panga (ISB)
Characterizing clinically relevant "Borrelia Burgdorferi" isolates in the era of proteogenomics
Deanna Plubell (UW)
Detecting peptide level changes in cerebrospinal fluid proteome of neurodegenerative disease by DIA
Adam Swensen (PNNL)
Nanoproteomic Characterization of Functional Dysregulation in Islets of Pre-Type 1 Diabetic Patients
Lightning Talk: John Cha (Providence)
Highly sensitive detection of immune checkpoint drugs in blood via nSMOL LC-MS assay
Session 4: Computational Proteomics
Chair: Eric Deutsch (ISB)
William Noble (UW)
A learned embedding for efficient joint analysis of millions of mass spectra
David Shteynberg (ISB)
Computing Information Content of PTM Localization with PTMProphet
Yang Lu (UW)
DIASibling: Learning to detect sibling peptide pairs in DIA mass spectrometry data
Brian Searle (ISB)
Building DIA MS libraries for non-model organisms with empirically corrected peptide predictions
Lightning Talk: Andy Lin (UW)
Targeted database search strategies: Searching only for relevant peptides
Lightning Talk: Luis Mendoza (ISB)
Integration of Known Variants and Modifications from PEFF into the Trans-Proteomic Pipeline
Lightning Talk: Seth Just (Proteome Software)
Influence of Library Selection for Proteomics Experiments on the Accuracy of Error Rate Estimation
Lightning Talk: Richard Johnson (UW)
Assessing protein sequence database suitability using de novo sequencing
Wine and Tapas Reception with Posters


We would like to thank the generous sponsorship received from the following organizations for the 2019 Cascadia Proteomics Symposium.

If your company is interested in becoming a symposium sponsor for 2019, please contact ( for details.

Or click here to sponsor now!




Sponsors receive exclusive recognition in the promotional materials, and at the beginning, during, and at the conclusion of the symposium.


Updated January 27, 2020

ISB has established accounts with some of the following hotels. To reserve a room through the ISB preferred hotels, simply call the reservation line of the specified hotel s and mention the ISB preferred rate. Note that availability is limited, and the rooms that can be booked at the preferred rate may sell out.

Before booking at ISB prices, check current street prices for rooms at, which are sometimes better. But check the reviews of any hotels not listed below, as there are some unpleasant hotels in the area.

Pan Pacific Seattle
ISB rate: $215 per night
Limited availability at discount rate
Distance from ISB: .5 mi.
2125 Terry Avenue
Seattle, WA 98121
Call (206) 264-8111 or email
EVEN Hotels / Staybridge Suites
ISB Rate: $165 per night
Distance from ISB: .3 mi.
527 Fairview Ave North
Seattle, WA 98191
Institute for Systems Biology EVEN Hotels or
Institute for Systems Biology Staybridge Suites or
Call (206) 254-0500 (corporate acct # 786922094)

Silver Cloud Inn Lake Union
ISB rate: 8% corporate discount
Limited availability at discount rate
Distance from ISB: .8 mi.
1150 Fairview Ave North
Seattle, WA 98109 Reservations:
Call (206) 812-4902 or email
Griselda Del Torro at

Other hotels near ISB

Moxy Seattle Downtown
Distance from ISB: 450 ft
$204 per night
1016 Republican St, Seattle 98109
Holiday Inn Seattle Downtown -- Lake Union
Distance from ISB: .4 mi
$118 per night
211 Dexter Ave N, Seattle 98109
La Quinta Inn by Wyndham Seattle Downtown
Distance from ISB: .5 mi
$159 per night
2224 8th Ave, Seattle, 98121
Civic Hotel
Distance from ISB: .6 mi
$140 per night
325 7th Ave N, Seattle 98109
Travelodge Seattle by The Space Needle
Distance from ISB: .7 mi
$122 per night
200 6th Ave North, Seattle 98109

For questions or assistance, please contact Theresa Davis at or by phone at (206) 732-1484.

Executive Committee

Chair: Robert L Moritz, Ph.D.
Proteomics Research Laboratory
Institute for Systems Biology, Seattle, WA, USA
Fields of interest: Protein Biochemistry, proteomics, mass spectrometry, bioinformatics, chromatography.

Vice Chair: Eric W Deutsch, Ph.D
Senior Research Scientist
Institute for Systems Biology, Seattle, WA, USA
Fields of Interest: Bioinformatics and integration of data for systems biology research, with a focus on proteomics. Head, Peptide Atlas Project.

Finance: Jim Kapron, Ph.D.
Technical Sales Representative -- Pacific Northwest
Mass Spectrometry
Bruker Ltd.

Kristin Burnum-Johnson, Ph.D.
Senior Scientist, Integrative Omics Group, Biological Sciences Division
Pacific Northwest National Laboratory, Richland, WA
Fields of interest: Proteomics, Lipidomics, Metabolomics

Matt Bush, Ph.D.
Assistant Professor, Department of Chemistry,
University of Washington, Seattle, WA
Fields of interest: Bioanalytical and Biophysical Chemistry

Haiwei Gu, Ph.D.
Northwest Metabolomics Research Center
University of Washington, Seattle, WA, USA
Fields of interest: Metabolomics, mass spectrometry, disease diagnosis, cell metabolism, bioinformatics

Wei-Jun Qian, Ph.D.
Senior Staff Scientist, Integrative Omics Group, Biological Sciences Division
Pacific Northwest National Laboratory, Richland WA
Field of Interest: Quantitative Proteomics, Posttranslational modifications, Redox proteomics, Diabetes.

Dan Raftery
Professor, Dept. of Anesthesiology and Pain Medicine, University of Washington
Director, Northwest Metabolomics Research Center
University of Washington, Seattle WA
Fields of interest: Metabolomics, mass spectrometry, NMR, bioinformatics, cancer metabolism

Martin Sadilek, Ph.D.
Mass Spectrometry Facility Manager
University of Washington, Seattle, WA
Fields of interest: Mass Spectrometry, Metabolomics, Lipidomics, Instrumentation, Fundamentals in analytical chemistry: separation techniques

Judit Villen, Ph.D.
Department of Genome Sciences
University of Washington, Seattle, WA, USA
Fields of interest: Proteomics, systems biology, mass spectrometry, cellular signaling, post-translational modifications, protein chemistry