Seattle, WA
July 8 - 9, 2019

About

The ninth annual Cascadia Proteomics Symposium brings together Proteomics Researchers from the Northwest region, Washington, Oregon, and British Columbia, to discuss current Proteomics Research, get to know each other better, share ideas and foster collaboration within this region. The program includes interactive oral and discussion sessions, as well as poster presentations with appetizers, wine and cheese sessions to foster mingling.

The 2019 symposium will return to the Institute for Systems Biology and will be held July 8-9. We look forward to seeing everyone again soon!


Register for Symposium                    Submit an Abstract

Program

Monday, July 8
Tuesday, July 9
Posters
800
Registration & Continental Breakfast
845
Welcome
Chair: Rob Moritz (ISB)
850
Keynote
Alexey Nesvizhskii (U Michigan)
Applications of Ultrafast Database Searching in Proteomics and Proteogenomics
935
Session 1: Systems Biology
Chair: Chris Barnes (Novo Nordisk)
935
Mark Gillespie (ISB)
A systems approach to quantifying transcriptional regulation in atherosclerosis
1000
Marli Vlok (UBC)
Positional proteomic analysis reveals novel cleavage products that promote enterovirus infection.
1025
Lightning Talk: Juan Chavez (UW)
Systems structural biology of the heart: Impact of acetylation on protein conformations/interactions
1030
Lightning Talk: Clint Vorauer (UW)
Biophysical Properties of Refractile Bodies
1035
Break
1105
Session 2: Degradomics and PTMs
Chair: Alexey Nesvizhskii (U Michigan)
1105
Daniele Canzani (UW)
Degronomics: Integrative Mass Spectrometry for Identifying Cellular E3 Ligase interactions
1130
Nestor Solis (UBC)
TAILS terminomics, shotgun proteomics and transcriptomics analysis of macrophage differentiation
1155
Abhigya Mookherjee (UW)
Hybrid mass spectrometric-based methods for distinguishing isomeric oligosaccharides
1220
Lightning Talk: Anthony Valente (UW)
Towards targeted phosphoproteomics by machine learning
1225
Lightning Talk: Christopher Adams (Bruker)
Identification and Quantitation of Phosphopeptide Positional Isomers using TIMS and PASEF
1230
Lightning Talk: Drake Russell (UW)
An Exploration of the Post Translational Structure of a Novel S-Methyltransferase
1235
Lightning Talk: Alex Zelter (UW)
Elucidating protein-xenobiotic interactions by mass spectrometry
1240
Lunch
1350
Session 3: Disease Proteomics
Chair: Wei-Jun Qian (PNNL)
1350
Phillipp Lange (UBC)
The first 50 cases in BRAvE: Using genomics and proteomics to advance pediatric precision oncology
1415
Jaipalreddy Panga (ISB)
Characterizing clinically relevant "Borrelia Burgdorferi" isolates in the era of proteogenomics
1440
Deanna Plubell (UW)
Detecting peptide level changes in cerebrospinal fluid proteome of neurodegenerative disease by DIA
1505
Adam Swensen (PNNL)
Nanoproteomic Characterization of Functional Dysregulation in Islets of Pre-Type 1 Diabetic Patients
1530
Lightning Talk: John Cha (Providence)
Highly sensitive detection of immune checkpoint drugs in blood via nSMOL LC-MS assay
1535
Break
1600
Session 4: Computational Proteomics
Chair: Eric Deutsch (ISB)
1600
William Noble (UW)
A learned embedding for efficient joint analysis of millions of mass spectra
1625
David Shteynberg (ISB)
Computing Information Content of PTM Localization with PTMProphet
1650
Yang Lu (UW)
DIASibling: Learning to detect sibling peptide pairs in DIA mass spectrometry data
1715
Brian Searle (ISB)
Building DIA MS libraries for non-model organisms with empirically corrected peptide predictions
1740
Lightning Talk: Andy Lin (UW)
Targeted database search strategies: Searching only for relevant peptides
1745
Lightning Talk: Luis Mendoza (ISB)
Integration of Known Variants and Modifications from PEFF into the Trans-Proteomic Pipeline
1750
Lightning Talk: Seth Just (Proteome Software)
Influence of Library Selection for Proteomics Experiments on the Accuracy of Error Rate Estimation
1755
Lightning Talk: Richard Johnson (UW)
Assessing protein sequence database suitability using de novo sequencing
1800
Wine and Tapas Reception with Posters

Sponsors

We would like to thank the generous sponsorship received from the following organizations for the 2019 Cascadia Proteomics Symposium.

If your company is interested in becoming a symposium sponsor for 2019, please contact (Cascadia@systemsbiology.org) for details.

Or click here to sponsor now!


                  

                  

                  

Sponsors receive exclusive recognition in the promotional materials, and at the beginning, during, and at the conclusion of the symposium.

Accommodations

Updated April 1, 2019

ISB has established accounts with some of the following hotels. To reserve a room through the ISB preferred hotels, simply call the reservation line of the specified hotel s and mention the ISB preferred rate. Note that availability is limited, and the rooms that can be booked at the preferred rate may sell out.

Before booking at ISB prices, check current street prices for rooms at hotels.com, which are sometimes better. But check the reviews of any hotels not listed below, as there are some unpleasant hotels in the area.

Pan Pacific Seattle
ISB rate: $255 per night
Distance from ISB: .5 mi.
2125 Terry Avenue
Seattle, WA 98121
Tel: 206-264-8111
Fax: 206-654-5049
www.panpacific.com/ISB
EVEN Hotels / Staybridge Suites
ISB Rate: $249 per night
Distance from ISB: .3 mi.
Email:dorene.kriekenbeekdavis@ihg.com
Tel : ( 206 ) 340-8432
Ask for ISB-Cascadia Rate
527 Fairview Ave North
Seattle, WA 98191
EvenHotel.com StaybridgeSuites.com

Silver Cloud Inn Lake Union
ISB Price: $249 per night
Ask for ISB corporate, limited availability
Distance from ISB: .8 mi.
1150 Fairview Ave North
Seattle, WA 98109
Tel: (800) 330-5812
www.silvercloud.com
UW Guest Housing
UW Guest Housing is a low cost option. A bus would be required to get to south lake union.
Sponsorship by a UW faculty member is required. Contact Theresa.Davis@systemsbiology.org for more information about how to book this option.
General prices: $55-98 per night.

College Inn Seattle
General rates: Starts at $105 per night
Distance from ISB: 2.9 mi.
4000 University Way NE
Seattle, WA 98105
Tel : (206) 633-4441
Fax : (206) 547-1335
mgr@collegeinnseattle.com
http://www.collegeinnseattle.com
Rather spartan but okay accomodations 3 miles away
But the price is nice.
Bus route #70 can be taken to get to ISB.

For questions or assistance, please contact Theresa Davis at Theresa.Davis@systemsbiology.org or by phone at (206) 732-1484.

Executive Committee

Chair: Robert L Moritz, Ph.D.
Proteomics Research Laboratory
Institute for Systems Biology, Seattle, WA, USA
Fields of interest: Protein Biochemistry, proteomics, mass spectrometry, bioinformatics, chromatography.


Vice Chair: Eric W Deutsch, Ph.D
Senior Research Scientist
Institute for Systems Biology, Seattle, WA, USA
Fields of Interest: Bioinformatics and integration of data for systems biology research, with a focus on proteomics. Head, Peptide Atlas Project.


Finance: Jim Kapron, Ph.D.
Technical Sales Representative -- Pacific Northwest
Mass Spectrometry
Bruker Ltd.


Kristin Burnum-Johnson, Ph.D.
Senior Scientist, Integrative Omics Group, Biological Sciences Division
Pacific Northwest National Laboratory, Richland, WA
Fields of interest: Proteomics, Lipidomics, Metabolomics


Matt Bush, Ph.D.
Assistant Professor, Department of Chemistry,
University of Washington, Seattle, WA
Fields of interest: Bioanalytical and Biophysical Chemistry


Haiwei Gu, Ph.D.
Northwest Metabolomics Research Center
University of Washington, Seattle, WA, USA
Fields of interest: Metabolomics, mass spectrometry, disease diagnosis, cell metabolism, bioinformatics


Wei-Jun Qian, Ph.D.
Senior Staff Scientist, Integrative Omics Group, Biological Sciences Division
Pacific Northwest National Laboratory, Richland WA
Field of Interest: Quantitative Proteomics, Posttranslational modifications, Redox proteomics, Diabetes.


Dan Raftery
Professor, Dept. of Anesthesiology and Pain Medicine, University of Washington
Director, Northwest Metabolomics Research Center
University of Washington, Seattle WA
Fields of interest: Metabolomics, mass spectrometry, NMR, bioinformatics, cancer metabolism


Martin Sadilek, Ph.D.
Mass Spectrometry Facility Manager
University of Washington, Seattle, WA
Fields of interest: Mass Spectrometry, Metabolomics, Lipidomics, Instrumentation, Fundamentals in analytical chemistry: separation techniques


Judit Villen, Ph.D.
Department of Genome Sciences
University of Washington, Seattle, WA, USA
Fields of interest: Proteomics, systems biology, mass spectrometry, cellular signaling, post-translational modifications, protein chemistry